DreamWeaver. Very easy to use and it works great on Macs.
Just use N-Vu. It is a free website creator that is as easy to use as a word processor. Just Google it. While you can just use its in its normal view, if you know HTML you can take it a lot further.
I’m a big fan of CMS sites. This allows you to create a turnkey site with your own feel. They come in ASP and PHP as far as I know. I use Drupal, it’s so easy to build a site and you can download templates or customize your own. Dreamweaver is a good sweet to use to customize the templates.